Genome-wide efficient mixed-model analysis for association studies
نویسندگان
چکیده
منابع مشابه
An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies
MOTIVATION In genome-wide association studies (GWAS) of complex diseases, genetic variants having real but weak associations often fail to be detected at the stringent genome-wide significance level. Pathway analysis, which tests disease association with combined association signals from a group of variants in the same pathway, has become increasingly popular. However, because of the complexiti...
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OF THE DISSERTATION Efficient Design and Analysis of Genome-wide Association Studies
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2012
ISSN: 1061-4036,1546-1718
DOI: 10.1038/ng.2310